PNC-27 Peptide
PNC-27 Peptide
PNC-27 is an anticancer peptide derived from the p53 tumor suppressor protein that selectively kills cancer cells by binding to HDM-2 in their membranes, triggering transmembrane pore formation and cell lysis without harming normal cells. It has demonstrated efficacy against multiple cancer types, including chemotherapy-resistant ovarian cancer, leukemia, and breast carcinoma, both in vitro and in vivo studies.
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